We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
| Structure | Details |
|---|---|
|
|
Product Name: (2R,3R,4S,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((benzoyloxy)methyl)-4-fluorotetrahydrofuran-3-yl benzoate Order number: 212099 CAS: 135473-17-5 Purity: 96% Appearance: n.a. MF: C31H24FN5O6 MW: 581.6 MP: n.a. oC Description: Useful building block for nucleoside and nucleotide chemistry |
|
|
Product Name: 3-carbamoyl-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium chloride Order number: 212100 CAS: 23111-00-4 Purity: 98% Appearance: WHITE POWDER MF: C11H15ClN2O5 MW: 290.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
|
|
Product Name: (2S,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-carboxylic acid Order number: 212101 CAS: 15596-14-2 Purity: 95% Appearance: n.a. MF: C10H11N5O6 MW: 297.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
|
|
Product Name: Guanosine, 5'-amino-5'-deoxy- Order number: 212102 CAS: 4099-84-7 Purity: 95% Appearance: SOLID MF: C10H14N6O4 MW: 282.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
|
|
Product Name: Guanosine, 5'-deoxy-5'-iodo- Order number: 212103 CAS: 68200-68-0 Purity: 95% Appearance: n.a. MF: C10H12IN5O4 MW: 393.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
|
|
Product Name: Adenosine, 2'-deoxy-3',5'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]- Order number: 212105 CAS: 51549-32-7 Purity: 98% Appearance: SOLID MF: C22H41N5O3Si2 MW: 479.8 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |