We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-D-erythro-pen Order number: 212106 CAS: 1193165-26-2 Purity: 98% Appearance: n.a. MF: C22H18Cl2N4O6 MW: 505.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5-(Methoxycarbonylmethyl)-2-thiouridine Order number: 212108 CAS: 20299-15-4 Purity: 95% Appearance: n.a. MF: MW: MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoro-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one Order number: 212109 CAS: 952429-17-3 Purity: 95% Appearance: n.a. MF: C11H12FN3O5 MW: 285.2 MP: n.a. oC Description: Useful building block for nucleoside and nucleotide chemistry |
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Product Name: 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine Order number: 212116 CAS: 81256-89-5 Purity: 98% Appearance: n.a. MF: C41H51N5O8Si MW: 770 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2'-Deoxypseudouridine Order number: 212119 CAS: 39967-60-7 Purity: 98% Appearance: WHITE POWDER MF: C9H12N2O5 MW: 228.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Thiotolyl b-D-ribofuranoside Order number: 212120 CAS: 1131610-84-8 Purity: 98% Appearance: SOLID MF: C12H16O4S MW: 256.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |