We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 2 -O-Methyl-2-O-ethyluridine Order number: 212121 CAS: 1352173-49-9 Purity: 97% Appearance: SOLID MF: C12H18N2O6 MW: 286.3 MP: n.a. oC Description: Useful building block for nucleoside and nucleotide chemistry |
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Product Name: N2,2'-O-Dimethylguanosine Order number: 212122 CAS: 135023-21-1 Purity: 98% Appearance: SOLID MF: C12H17N5O5 MW: 311.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: ((2R,3R,4R,5R)-3-(Benzoyloxy)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methyltetrahydrofuran-2-yl)methylbenzoate Order number: 212129 CAS: 1496551-71-3 Purity: 98% Appearance: n.a. MF: C24H20ClN2O7- MW: 483.9 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5-Fluorouridine Order number: 212132 CAS: 77180-80-4 Purity: 95% Appearance: SOLID MF: C9H11FN2O6 MW: 262.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: S-Adenosyl-L-methionine tosylate Order number: 212133 CAS: 71914-80-2 Purity: ?80% Appearance: n.a. MF: C22H29N6O7S2 MW: 553.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: (3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dibenzyloxy-5-(benzyloxymethyl)tetrahydrofuran-2-ol Order number: 212135 CAS: 1355049-94-3 Purity: 98% Appearance: SOLID MF: C32H32N4O5 MW: 552.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |