Amino Acids and Nucleosides

We offer FMOC-protected unnatural amino acids for synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.

We offer nucleosides with modifications at the pyrimidine or purine base, such as 6- Thioguanine, 7-Deazaadenine, 7-Deazaguanine, 8-Azidoadenine, 8-Bromoinosine and 8- Iodoadenine, and at the sugar such as 5'-Azido-5'-deoxythymidine, 2'-Azido-2'-deoxyuridine and 2'-Azido-2'-deoxy-5-methyl uridine.

  • Amino Acids for Stapled Peptides
  • 2-Methylated Amino Acids
  • Peptide Labeling
  • Other Unnatural Amino Acids
  • Modified Nucleosides
  • HNA Precursors
  • Morpholino Nucleosides
  • Other Nucleosides & Intermediates
  • Structure Details
    Product Name: 2'-O-Methyladenosine
    Order number: 201289
    CAS: 2140-79-6
    Purity: >=95%
    Appearance: solid
    MF: C11H15N5O4
    MW: 281.272
    MP: n.a. oC

    Description:
    This is a nucleoside intermediate and may be used for activity studies.
    Product Name: 5'-Chloro-5'-deoxyadenosine
    Order number: 201290
    CAS: 892-48-8
    Purity: >=95%
    Appearance: solid
    MF: C10H12ClN5O3
    MW: 285.688
    MP: n.a. oC

    Description:
    This is a nucleoside intermediate and may be used for activity studies.
    Product Name: 2-Thiothymidine
    Order number: 201294
    CAS: 28585-51-5
    Purity: >=95%
    Appearance: solid
    MF: C10H14N2O4S
    MW: 258.292
    MP: n.a. oC

    Description:
    Thiothymidines have been used for anti-herpesvirus studies.
    Product Name: 2',3'-Didehydro-2',3'-dideoxyuridine
    Order number: 201297
    CAS: 5974-93-6
    Purity: >=95%
    Appearance: solid
    MF: C9H10N2O4
    MW: 210.189
    MP: n.a. oC

    Description:
    The dideoxyuridine nucleosides have found broad antiviral activities.
    Product Name: 2'-O-(2-Methoxyethyl)-5'-O-bis(4-methoxypheny)phenylmethy-5-methyluridine
    Order number: 201300
    CAS: 163759-50-0
    Purity: >=95%
    Appearance: solid
    MF: C34H38N2O9
    MW: 618.683
    MP: n.a. oC

    Description:
    This is a nucleoside intermediate.
    Product Name: (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-4-pentenoic acid
    Order number: 201306
    CAS: 288617-71-0
    Purity: >=95%
    Appearance: solid
    MF: C21H21NO4
    MW: 351.402
    MP: n.a. oC

    Description:
    The alkenyl side chain of this product, Fmoc-protected and solid-phase amenable, can be tied (stapled) with another adjacent alkenyl side chain pre-existed on the peptide backbone via a ring-closure metathesis process.