We offer FMOC-protected unnatural amino acids for synthesis of peptides for biological
research and pharmaceutical development. By introducing conformational constraints, the
peptides may have one or several of the following features: 1. enhancement of peptide
backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular
permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic
breakdown.
We offer nucleosides with modifications at the pyrimidine or purine base, such as 6-
Thioguanine, 7-Deazaadenine, 7-Deazaguanine, 8-Azidoadenine, 8-Bromoinosine and 8-
Iodoadenine, and at the sugar such as 5'-Azido-5'-deoxythymidine, 2'-Azido-2'-deoxyuridine
and 2'-Azido-2'-deoxy-5-methyl uridine.
Structure | Details |
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Product Name: 2'-O-Methyladenosine Order number: 201289 CAS: 2140-79-6 Purity: >=95% Appearance: solid MF: C11H15N5O4 MW: 281.272 MP: n.a. oC Description: This is a nucleoside intermediate and may be used for activity studies. |
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Product Name: 5'-Chloro-5'-deoxyadenosine Order number: 201290 CAS: 892-48-8 Purity: >=95% Appearance: solid MF: C10H12ClN5O3 MW: 285.688 MP: n.a. oC Description: This is a nucleoside intermediate and may be used for activity studies. |
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Product Name: 2-Thiothymidine Order number: 201294 CAS: 28585-51-5 Purity: >=95% Appearance: solid MF: C10H14N2O4S MW: 258.292 MP: n.a. oC Description: Thiothymidines have been used for anti-herpesvirus studies. |
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Product Name: 2',3'-Didehydro-2',3'-dideoxyuridine Order number: 201297 CAS: 5974-93-6 Purity: >=95% Appearance: solid MF: C9H10N2O4 MW: 210.189 MP: n.a. oC Description: The dideoxyuridine nucleosides have found broad antiviral activities. |
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Product Name: 2'-O-(2-Methoxyethyl)-5'-O-bis(4-methoxypheny)phenylmethy-5-methyluridine Order number: 201300 CAS: 163759-50-0 Purity: >=95% Appearance: solid MF: C34H38N2O9 MW: 618.683 MP: n.a. oC Description: This is a nucleoside intermediate. |
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Product Name: (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-4-pentenoic acid Order number: 201306 CAS: 288617-71-0 Purity: >=95% Appearance: solid MF: C21H21NO4 MW: 351.402 MP: n.a. oC Description: The alkenyl side chain of this product, Fmoc-protected and solid-phase amenable, can be tied (stapled) with another adjacent alkenyl side chain pre-existed on the peptide backbone via a ring-closure metathesis process. |