We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: N5-[(Dimethylamino)iminomethyl]-L-ornithine Order number: 204400 CAS: 30315-93-6 Purity: >=95% Appearance: solid MF: C8H18N4O2 MW: 202.258 MP: n.a. oC Description: This amino acid once incorporated in peptide may enhance its cellular permeability. |
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Product Name: N5-[(Dimethylamino)iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine Order number: 204401 CAS: 268564-10-9 Purity: >=95% Appearance: solid MF: C23H28N4O4 MW: 424.501 MP: n.a. oC Description: Fmoc-protected solid-phase amenable amino acid is used to enhance peptide function/property. |
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Product Name: (R)-4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-amino-5-oxopentanoic acid Order number: 204404 CAS: 292150-20-0 Purity: >=95% Appearance: solid MF: C20H20N2O5 MW: 368.389 MP: n.a. oC Description: Fmoc-protected solid-phase amenable amino acid is used to enhance peptide function/property. |
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Product Name: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-8-(tert-butoxy)-8-oxooctanoic acid Order number: 204410 CAS: 276869-41-1 Purity: >=95% Appearance: solid MF: C27H33NO6 MW: 467.562 MP: n.a. oC Description: Fmoc/Boc-protected solid-phase amenable steric amino acid is used orthogonally to enhance peptide function. |
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Product Name: (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-Hexanedioic acid-6-(tert-butyll) ester Order number: 204411 CAS: 159751-47-0 Purity: >=95% Appearance: solid MF: C25H29NO6 MW: 439.508 MP: n.a. oC Description: Fmoc/Boc-protected solid-phase amenable steric amino acid is used orthogonally to enhance peptide function. |
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Product Name: (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2,2-dimethyl-1,3-Benzodioxole-5-propanoic acid Order number: 204420 CAS: 852288-18-7 Purity: >=95% Appearance: solid MF: C27H25NO6 MW: 459.498 MP: n.a. oC Description: Fmoc-protected solid-phase amenable amino acid is used to enhance peptide function/property. |