We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Ethyl (3-R,S)-hydroxyl-2,2-difluoro-3-(2,2-dimethyldioxolan-4-yl)propionate Order number: RT-R07-142 CAS: 95058-92-7 Purity: >=95% Appearance: solid MF: C10H16F2O5 MW: 254.23 MP: n.a. oC Description: This is a useful difluorosugar moiety for making antiviral nucleosides. |
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Product Name: DMT-dA(Bz)-CE Order number: 204720 CAS: 98796-53-3 Purity: 98% Appearance: solid MF: C47H52N7O7P MW: 857.95 MP: n.a. oC Description: This is a useful building block in oligonucleotide synthesis on solid phase both for research and commercial drug development. |
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Product Name: DMT-dG(iBu)-CE Order number: 204721 CAS: 93183-15-4 Purity: 98% Appearance: solid MF: C44H54N7O8P MW: 839.93 MP: n.a. oC Description: This is a useful building block in oligonucleotide synthesis on solid phase both for research and commercial drug development. |
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Product Name: DMT-dG(dmf)-CE Order number: 204722 CAS: 330628-04-1 Purity: 98% Appearance: solid MF: C43H53N8O7P MW: 824.92 MP: n.a. oC Description: This is a useful building block in oligonucleotide synthesis on solid phase both for research and commercial drug development. |
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Product Name: DMT-dC(Bz)-CE Order number: 204723 CAS: 102212-98-6 Purity: 98% Appearance: solid MF: C46H52N5O8P MW: 833.92 MP: n.a. oC Description: This is a useful building block in oligonucleotide synthesis on solid phase both for research and commercial drug development. |
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Product Name: DMT-dC(Ac)-CE Order number: 204724 CAS: 154110-40-4 Purity: 98% Appearance: solid MF: C41H50N5O8P MW: 771.85 MP: n.a. oC Description: This is a useful building block in oligonucleotide synthesis on solid phase both for research and commercial drug development. |