Amino Acids and Nucleosides

We offer FMOC-protected unnatural amino acids for synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.

We offer nucleosides with modifications at the pyrimidine or purine base, such as 6- Thioguanine, 7-Deazaadenine, 7-Deazaguanine, 8-Azidoadenine, 8-Bromoinosine and 8- Iodoadenine, and at the sugar such as 5'-Azido-5'-deoxythymidine, 2'-Azido-2'-deoxyuridine and 2'-Azido-2'-deoxy-5-methyl uridine.

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Structure	Details
	Product Name: Droxidopa Order number: RT-R04-029 CAS: 23651-95-8 Purity: >=95% Appearance: solid MF: C9H11NO5 MW: 213.189 MP: 225 oC Description: This compound can be a useful chiral starting material. Biologically, it is a substrate of dopodehydroxylase to convert to norepinephrine within sympathetic terminals. Login to check availability and price information.
	Product Name: Methyl-(2s,4s)-4-fluoro-2-prolinate Order number: RT-R06-362 CAS: 58281-79-1 Purity: >=95% Appearance: solid MF: C6H11ClFNO2 MW: 183.607 MP: n.a. oC Description: The fluorine with strong inductive effect can enforce a particular ring pucker and accelerate cis/trans prolyl peptide bond isomerization, thereby providing conformational stability for peptides and proteins. Login to check availability and price information.
	Product Name: 6-Azaindole Order number: RT-R06-499 CAS: 271-29-4 Purity: >=95% Appearance: solid MF: C7H6N2 MW: 118.139 MP: n.a. oC Description: Azaindoles (pyrrolopyridine) are indole bioisosteres for pharmaceutical optimization, for binding, solubility, and ADME properties. Login to check availability and price information.
	Product Name: Ethyl (3-R,S)-hydroxyl-2,2-difluoro-3-(2,2-dimethyldioxolan-4-yl)propionate Order number: RT-R07-142 CAS: 95058-92-7 Purity: >=95% Appearance: solid MF: C10H16F2O5 MW: 254.23 MP: n.a. oC Description: This is a useful difluorosugar moiety for making antiviral nucleosides. Login to check availability and price information.

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